No, Provitalize ingredients are not methylated.
That said, Provitalize had been designed for maximum absorption in mind.
Provitalize contains BioPerine (black pepper piperine extract) to greatly boost the absorption of curcumin. This matters as curcumin naturally has very low bioavailability.
It uses DRCaps (delayed release capsules) to ensure its probiotic strains don't get killed by our harsh stomach acids and can reach the small intestines, which overall helps the gut to absorb Provitalize ingredients better.